When you see someone with bright ginger or auburn hair, it often turns heads. Red hair is striking, rare, and sometimes even comes with stereotypes or myths attached to it. But behind the unique shade lies fascinating science — from genetics to biochemistry to evolution. Let’s break down why some people have red hair, what genes are responsible, and why it is so uncommon.
	
	
	
Eumelanin: This pigment is responsible for black and brown shades. Higher levels of eumelanin mean darker hair.
Pheomelanin: This pigment has a reddish-yellow hue. People with a lot of pheomelanin have red, orange, or golden tones in their hair.
Most people have a mixture of both, but the balance between eumelanin and pheomelanin is what creates different hair colours. For redheads, pheomelanin dominates while eumelanin is low.
The main genetic factor that makes someone a natural redhead is the MC1R gene (short for melanocortin 1 receptor). This gene acts like a switch that tells pigment-producing cells, called melanocytes, whether to make eumelanin or pheomelanin.
In people with a fully functioning MC1R gene, the body mostly produces eumelanin, leading to brown or black hair.
In people with variations (mutations) in the MC1R gene, the switch doesn’t work properly. Instead of producing more eumelanin, their cells default to producing pheomelanin. The result is red hair.
Scientists have discovered over a dozen different MC1R variants associated with red hair, freckles, and fair skin. To actually have naturally red hair, a person usually needs to inherit two copies of a non-functioning MC1R variant — one from each parent. This is why red hair often “skips a generation.” Parents without red hair can still carry the gene and pass it on to their children.
One theory is that in cloudier regions with less sunlight, red hair and pale skin provided an evolutionary advantage. Fair skin, often linked to red hair, is better at producing vitamin D in low-light environments. This could explain why the trait persisted in these populations even though it is relatively rare worldwide.
Interestingly, research shows that people with MC1R variants may also have a slightly higher risk of developing skin cancers like melanoma, even without heavy sun exposure. That’s because pheomelanin itself may contribute to oxidative stress in skin cells. This makes sunscreen and careful sun protection especially important for redheads.
Pain sensitivity: Some studies suggest that redheads are more sensitive to certain types of pain and may require more anesthesia during surgery.
Temperature perception: There is evidence that redheads may feel hot and cold differently compared to non-redheads.
Freckles: Many redheads have freckles because the same gene variations affect how melanin is distributed in the skin.
These links are still being studied, but they show that the genetics of hair colour can ripple through the body in surprising ways.
The truth is simple: red hair is the product of a genetic variant, a pigment imbalance, and an evolutionary story tied to sunlight and geography. While rare, it’s a brilliant example of how small changes in our DNA can create striking differences in appearance.